Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates
نویسندگان
چکیده
منابع مشابه
Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates.
Junctions at class switch recombination sites in the genome are characterized by a unique sequence feature. Nucleotide substitutions and small deletions are common on either of the two sides of the switch junction, but not on both together. We have previously reported an extrachromosomal substrate assay system for analyzing the recombination of class switch sequences. Here we have sequenced nin...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1996
ISSN: 1362-4962
DOI: 10.1093/nar/24.11.2104